Prevalence of Antiphospholipid Antibodies in Syrian Patients with Thrombosis
نویسندگان
چکیده مقاله:
Background: Antiphospholipid antibodies (aPL) are a heterogeneous family of anti-bodies associated with thrombosis and other complications. Objective: To study the prevalence of aPL in patients with thrombosis at Aleppo University Hospitals, Syria. Methods: One hundred and fifty-seven patients with venous and arterial thrombosis and 63 healthy controls were studied. Anticardiolipin antibodies (aCL) and Lupus antico-agulant (LA) were determined. Results: Thirty-four out of 157 (21.7%) patients with thrombosis had some type of aPL. aPL was also found in four healthy subjects (4/63=6.3%). Eighteen patients (11.5%) were positive for LA, 20 (12.7%) for aCL anti-bodies and 4 (2.6%) were positive for more than one aPL. Patients without risk factors for thrombosis and having positive aPL were 23/34 (67.7%). Fourteen out of 78 (17.9%) patients with arterial thrombosis, and 20/79 (25.3%) with venous thrombosis were positive for at least one aPL. Conclusion: Our study showed a significant preva-lence of aPL in patients with thrombosis. It seems that aPL is a risk factor for venous and arterial thrombosis, especially in patients with no conventional risk factors.
منابع مشابه
prevalence of antiphospholipid antibodies in syrian patients with thrombosis
background: antiphospholipid antibodies (apl) are a heterogeneous family of anti-bodies associated with thrombosis and other complications. objective: to study the prevalence of apl in patients with thrombosis at aleppo university hospitals, syria. methods: one hundred and fifty-seven patients with venous and arterial thrombosis and 63 healthy controls were studied. anticardiolipin antibodies (...
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BACKGROUND Antiphospholipid antibodies (aPL) are a heterogeneous family of antibodies associated with thrombosis and other complications. OBJECTIVE To study the prevalence of aPL in patients with thrombosis at Aleppo University Hospitals, Syria. METHODS One hundred and fifty-seven patients with venous and arterial thrombosis and 63 healthy controls were studied. Anticardiolipin antibodies (...
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عنوان ژورنال
دوره 6 شماره 3
صفحات 154- 159
تاریخ انتشار 2009-09-01
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